Infant Primate Research Laboratory
Research Protocol &Technician's Manual
A Guide to the Care, Feeding, & Evaluation
of Infant Monkeys
Gerald C. Ruppenthal & Gene P. Sackett
Second Edition
Supported by the
Center on Human Development and Disability (formerly the Child Development and Mental Retardation Center)
and the
Regional Primate Research Center
University of Washington
Table of Contents
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PART I: Research Protocols
- Introduction
- Maternal
and Fetal Blood and Amniotic Fluid
- Blood Draws and Assays
- Amniotic Fluid
- Maternal Prepartum Exams
- Maternal Status
- Labor
and Delivery
- A. Observations
- B. Infant Evaluation
- C. Procedures
- D. Placental Exam
- E. Guidelines for Surgical Termination of Pregnancy
- Infant Blood Draws
- Physical Growth and Development
- Tooth Eruption
- Anthropometrics and Radiographs
- Infant Status Checks
- Reflex Development
- Visual Acuity Assessment
- Recognition Memory
- Standardized Test of Visual Recognition
- Cross-Modal Recognition
- Motor Development
- Object Concept Protocol
- Home Cage Testing
- Home Cage Scoring System
- Sleep-Passive Category
- Stereotypy Category
- Exploration Category
- Play Category
- Disturbance-Fear Category
- Aggress-Threat Category
- Stereotypy and Fear-Disturb Category
- Playroom Testing
- The Four-Digit Coding System
- Social Behavior Coding System
- Wisconsin
General Testing Apparatus (WGTA)
- Problem 01—Black/White Adaptation
- Problem 02—Black/White Discrimination, White Rewarded
- Problem 03—Black/White Discrimination, Black Rewarded
- Problem 04—Black/White Reversal, White Previously Rewarded
- Problem 05—Black/White Reversal, Black Previously Rewarded
- Problem 06—Hamilton Search Adaptation
- Problem 07—Hamilton Search
- Problem 08—Hamilton Search Set Breaking
- Problem 09—Hamilton Search Forced Set Breaking
- Problem 10—Learning Set, A Rewarded
- Problem 11—Learning Set, B Rewarded
- Complex Concept Learning Protocol
- Phase 1—Adaptation
- Phase 2—Nonmatching to Sample
- Phase 3—Matching to Sample
- Phase 4—Conditional Nonmatching and Matching to Sample
- Phase 5—Delayed Nonmatching to Sample
- Adaptation to Group Housing
- Feeding and Housing Protocols
- Feeding
Protocol
- Housing
Schedule
PART II: Technicians' Guide
- Nursery Shift Protocols
- Shift-Dependent Responsibilities
- Start of Shift
- Main Feedings
- Midshift Feedings
- New Formula
- Putting Holes in Nipples
- Diurnal Measurements
- Births
- Feeding and Housing Schedules
- Laundry
- Sanitation
- Lab Security
- Protocols for Data Collection and Record Keeping
- Intake Records
- Shift Responsibilities—Weight
- Shift Responsibilities—Intakes
- Shift Responsibilities—Codes
- Further Examples of Feeding Protocols
- Example of an Animal Worksheet
- Special Procedures in the Nursery
- Low-Birth-Weight Infants
- Hypothermia
- Aspiration
- Gavage Feeding
- Intravenous Support
- Restraint Boards
- Oxygen
- Rectal Temperatures
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