AIDS-Related Diseases
Providing expertise and resources to better understand, prevent and treat HIV and AIDS.
Nonhuman Primate Systems Biology
Using systems biology and computational modeling to understand infection and immunology.
Global Programs
Focusing on conservation biology, field study training and emerging infectious diseases.
Neuroscience
Using the primate model to answer questions about the nervous system, vision and more.
Reproductive & Developmental Sciences
Exploring reproductive biology, stem cell research and cognitive development.
Evolutionary Emergence of Infectious Diseases
Understanding how interspecies interaction leads to the emergence of disease.
Venture/Pilot Program
Providing specialized facilities, expertise and support to investigators with approved projects.

Division of Reproductive & Developmental Sciences

The primary goal of the Division of Reproductive and Developmental  Sciences is to provide critical services to investigators using nonhuman primates  for studies in maternal and children’s health. Services within the division are provided to investigators through the use of the Infant Primate Research Lab (IPRL). The IPRL continues to be supported as a core  facility of both the Primate Center and the Center on Human Development and Disability (CHDD). For over 40 years, the overall objective of the lab has been to provide a range of technical services, facilities, and equipment  to meet both the clinical care and research needs of investigators. The clinical and research operations in  the lab are closely tied due to the nature of the research conducted in the facility. The efforts are also closely integrated with activities and support from the other units within the Division of Primate Resources  and are utilized by nearly all of the scientific units.

The services provided by the division through the IPRL meet the  objectives of the National Primate Research Center (NPRC) Program. Consultation services regarding appropriate  research designs, methods, and data analysis techniques are provided to assist investigators who are  unfamiliar with the unique characteristics of nonhuman primate research. Laboratory personnel provide training and  on-site supervision to project staff conducting research in the laboratory. Personnel also provide training  for undergraduate, graduate and postgraduate students. This includes training in the safe handling of animals as well  as training on the various developmental assessments. Laboratory personnel also work with  individual investigators to provide innovative responses as new areas of research develop. These services provide unique capabilities for translational research requiring pregnant  females, gestational-age-known fetuses and infant nonhuman primates. For example, translational research related to  the prevention of premature delivery related to maternal infection, intervention strategies for severe  asphyxia at birth, and maternal-fetal transmission of SHIV were recently carried out by the IPRL. Studies conducted in the lab are very complex in their designs, take years to complete and require  extensive shared services. The services provided to investigators result in cost savings through shared access  to facilities, staff and equipment.

Costs for around-the-clock animal care services are included in the increased per diem rates for IPRL housed infants. Costs associated with research supported activities are recovered  through grant-support for IPRL staff involved in research training and testing.

Core Staff Scientists

Name
WaNPRC Division
Position
UW Department(s)
Thomas M. Burbacher

Reproductive &
Developmental Sciences
Core Staff ScientistDepartment of Environmental & Health Sciences
Michael Mustari
Neuroscience

Reproductive &
Developmental Sciences
Core Staff ScientistDepartment of Ophthalmology
Jim SackettReproductive &
Developmental Sciences (Emeritus)
Core Staff ScientistDepartment of Psychology

Research Scientists

Name
WaNPRC Division
Position
UW Department(s)
Eliza CurnowReproductive &
Developmental Sciences
Research Scientist